GBP5 antibody

Catalog No. ABIN7114836

This anti-GBP5 antibody is a Rabbit Polyclonal antibody detecting GBP5 in WB, ELISA, IHC, IF and FACS. Suitable for Human.

Quick Overview for GBP5 antibody (ABIN7114836)

Target: GBP5 (Guanylate Binding Protein 5 (GBP5))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GBP5 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS)

Product Details anti-GBP5 Antibody

Purpose: GBP5 antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: guanylate binding protein 5

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:2000, IHC: 1:20-1:200, IF: 1:20-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for GBP5

Target: GBP5 (Guanylate Binding Protein 5 (GBP5))

Alternative Name: GBP5

Background:

Synonyms: Guanylate-binding protein 5|GBP-TA antigen|GTP-binding protein 5 (GBP-5)|Guanine nucleotide-binding protein 5|GBP5

Background: As an activator of NLRP3 inflammasome assembly, plays a role in innate immunity and inflammation. Promotes selective NLRP3 inflammasome assembly in response to microbial and soluble, but not crystalline, agents(PubMed:22461501). Hydrolyzes GTP, but in contrast to other family members, does not produce GMP(PubMed:20180847).

Molecular Weight: 65 kDa, 55 kDa

Gene ID: 115362

UniProt: Q96PP8